A unique recombination event resulting in a C4A*Q0,C4B*Q0 double null haplotype.
نویسندگان
چکیده
منابع مشابه
A Unique Recombination Event Resulting in a C 4 A * QO , C 4 B * QO Double Null Haplotype
The fourth component of complement (C4) is encoded by two closely linked genes (C4A and C4B) within the MHC. Null alleles at either locus (C4AQO or C4BQO) are relatively common, occurring at the C4A locus in 10% of normal individuals and at the C4B locus in 16% of normal individuals. However, the presence of the double null haplotype (C4A * QO,B * QO) on the same chromosome is extremely rare. W...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1992
ISSN: 0021-9738
DOI: 10.1172/jci115978